Streamlined production of nanoparticles for optimized drug delivery
Phosphorex Inc. – a contract development and manufacturing organization specializing in the production of particle-based formulations – is using the Automated Nanoparticle (ANP) System from Particle Works to optimize its processes.
“The Particle Works team always listens to us, and works tirelessly to provide what we need.”
Dr Julia Rashba-Step, VP of R&D and Alliance Management at Phosphorex, commented:
“We help our clients with the development of nanomedicines by creating novel nanoparticles customized to individual project needs. Clients reach out to us at different stages of product development; some may need assistance in the early discovery phase while others already have a working formulation that they want to scale up. Our focus lies on process optimization, investigating different microfluidic parameters to achieve the ideal particle size, shape and structure, as well as improve targeting and drug encapsulation. The processes that we design must be robust and scalable and we therefore spent a significant amount of time searching for the optimal microfluidic system, choosing the ANP System from Particle Works.”
Julia continued: “The ANP system allows us to screen multiple formulations very quickly to achieve the target particle size and distribution; it is stable and ensures high consistency and reproducibility. The technology is easy to use and we’re so happy with the system that we have decided to act as a demonstration lab for Particle Works, offering training and technical support to help customers to advance their nanoparticle programs from proof-of-concept to the clinical development stage. The Particle Works team always listens to us, and works tirelessly to provide what we need. We enjoy working with them.”